Solid phase peptide synthesis by J. M. Stewart and J. D. Young
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چکیده
منابع مشابه
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متن کاملSolid-phase peptide synthesis and solid-phase fragment coupling mediated by isonitriles.
The synthesis of polypeptides on solid phase via mediation by isonitriles is described. The acyl donor is a thioacid, which presumably reacts with the isonitrile to generate a thio-formimidate carboxylate mixed anhydride intermediate. Applications of this chemistry to reiterative solid-phase peptide synthesis as well as solid-phase fragment coupling are described.
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ژورنال
عنوان ژورنال: Acta Crystallographica Section B Structural Crystallography and Crystal Chemistry
سال: 1970
ISSN: 0567-7408
DOI: 10.1107/s0567740870004193